The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice

Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical role in the fibrotic process. MicroRNA-29 (miR-29) has proved to alleviate the occurrence of PF by downregulating TGF-β/Smad3 signaling pathway. The miRNA a...

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Bibliographic Details
Main Authors: Yanzhen Yu, Xingzhi Liu, Zhe Zhao, Zhongjuan Xu, Yong Qiao, Yuanshuai Zhou, Hong Qiao, Junjie Zhong, Jianwu Dai, Guangli Suo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
pulmonary fibrosis
extracellular matrix
miR-29
exosome
collagen-binding domain
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.747223/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.747223/full

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