Chromatin phase separated nanoregions explored by polymer cross-linker models and reconstructed from single particle trajectories.

Phase separated domains (PSDs) are ubiquitous in cell biology, representing nanoregions of high molecular concentration. PSDs appear at diverse cellular domains, such as neuronal synapses but also in eukaryotic cell nucleus, limiting the access of transcription factors and thus preventing gene expre...

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Bibliographic Details
Main Authors: Andrea Papale, David Holcman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011794&type=printable