Increased Inhibition May Contribute to Maintaining Normal Network Function in the Ventral Hippocampus of a Fmr1-Targeted Transgenic Rat Model of Fragile X Syndrome

A common neurobiological mechanism in several neurodevelopmental disorders, including fragile X syndrome (FXS), is alterations in the balance between excitation and inhibition in the brain. It is thought that in the hippocampus, as in other brain regions, FXS is associated with increased excitabilit...

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Bibliographic Details
Main Authors: Leonidas J. Leontiadis, George Trompoukis, Panagiotis Felemegkas, Giota Tsotsokou, Athina Miliou, Costas Papatheodoropoulos
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/11/1598