Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in <i>Saccharomyces cerevisiae</i>

Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in <i>Saccharomyces cerevisiae</i>

Polyamines are essential biogenic poly-cations with important roles in many cellular processes and diseases such as cancer. A rate-limiting step early in the biosynthesis of polyamines is the conversion of ornithine to putrescine by the homodimeric enzyme ornithine decarboxylase (ODC). In a conserve...

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Bibliographic Details
Main Authors: Kai Halwas, Lennard-Maximilian Döring, Franziska Valentina Oehlert, R. Jürgen Dohmen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
polyamines
ornithine decarboxylase antizyme
hypusination
conditional mutants
DFMO
Oaz1
Online Access:https://www.mdpi.com/1422-0067/23/21/12972

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https://www.mdpi.com/1422-0067/23/21/12972

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