Robust formation of optimal single spheroids towards cost‐effective in vitro three‐dimensional tumor models

While useful for fundamental in vitro studies, monolayer cell cultures are not physiologically relevant. Spheroids, a complex three‐dimensional (3D) structure, more closely resemble in vivo tumor growth. Spheroids allow the results obtained relating to proliferation, cell death, differentiation, met...

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Bibliographic Details
Main Authors: Kinana Habra, Joshua R. D. Pearson, Stéphanie E. B. McArdle
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13614