Diffusion, crowding & protein stability in a dynamic molecular model of the bacterial cytoplasm.

A longstanding question in molecular biology is the extent to which the behavior of macromolecules observed in vitro accurately reflects their behavior in vivo. A number of sophisticated experimental techniques now allow the behavior of individual types of macromolecule to be studied directly in viv...

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Bibliographic Details
Main Authors: Sean R McGuffee, Adrian H Elcock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2832674?pdf=render