Intranasal B5 promotes mucosal defence against Actinobacillus pleuropneumoniae via ameliorating early immunosuppression

Intranasal B5 promotes mucosal defence against Actinobacillus pleuropneumoniae via ameliorating early immunosuppression

ABSTRACTActinobacillus pleuropneumoniae (APP) is an important pathogen of the porcine respiratory disease complex, which leads to huge economic losses worldwide. We previously demonstrated that Pichia pastoris-producing bovine neutrophil β-defensin-5 (B5) could resist the infection by the bovine int...

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Bibliographic Details
Main Authors: Jingsheng Huang, Weichao Kang, Dandan Yi, Shuxin Zhu, Yifei Xiang, Chengzhi Liu, Han Li, Dejia Dai, Jieyu Su, Jiakang He, Zhengmin Liang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Virulence
Subjects:
Actinobacillus pleuropneumoniae
bovine neutrophil β-defensin-5
mucosal defence
Group 3 innate lymphoid cells
immune suppression
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2024.2316459

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https://www.tandfonline.com/doi/10.1080/21505594.2024.2316459

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