Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity
Abstract Ligand-induced receptor dimerization or oligomerization is a widespread mechanism for ensuring communication specificity, safeguarding receptor activation, and facilitating amplification of signal transduction across the cellular membrane. However, cell-surface antigen-induced multimerizati...
| Những tác giả chính: | , , , , , , , , , , , , , , , |
|---|---|
| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
Nature Publishing Group
2023-12-01
|
| Loạt: | Signal Transduction and Targeted Therapy |
| Truy cập trực tuyến: | https://doi.org/10.1038/s41392-023-01686-z |