Regulating STING in health and disease
Abstract The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INterferon Genes (STING)”. STING has been found to mediate type I interferon response...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-06-01
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Series: | Journal of Inflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12950-017-0159-2 |