Regulating STING in health and disease

Abstract The presence of cytosolic double-stranded DNA molecules can trigger multiple innate immune signalling pathways which converge on the activation of an ER-resident innate immune adaptor named “STimulator of INterferon Genes (STING)”. STING has been found to mediate type I interferon response...

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Bibliographic Details
Main Authors: Yang Li, Heather L. Wilson, Endre Kiss-Toth
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Journal of Inflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12950-017-0159-2