Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross

Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross

The oligoadenylate-synthetase (Oas) gene locus provides innate immune resistance to virus infection. In mouse models, variation in the Oas1b gene influences host susceptibility to flavivirus infection. However, the impact of Oas variation on overall innate immune programming and global gene expressi...

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Bibliographic Details
Main Authors:	Richard Green, Courtney Wilkins, Sunil Thomas, Aimee Sekine, Duncan M. Hendrick, Kathleen Voss, Renee C. Ireton, Michael Mooney, Jennifer T. Go, Gabrielle Choonoo, Sophia Jeng, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Shannon McWeeney, Michael Gale Jr.
Format:	Article
Language:	English
Published:	Oxford University Press 2017-06-01
Series:	G3: Genes, Genomes, Genetics
Subjects:	Oas flavivirus viral infection innate immunity multiparental populations Multi-parent Advanced Generation Inter-Cross (MAGIC) MPP
Online Access:	http://g3journal.org/lookup/doi/10.1534/g3.117.041624

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