Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer
<p>Abstract</p> <p>Background</p> <p>Successful treatment of solid tumors relies on the ability of drugs to penetrate into the tumor tissue.</p> <p>Methods</p> <p>We examined the correlation of panitumumab (an anti-epidermal growth factor [EGFR]...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-07-01
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| Series: | Molecular Cancer |
| Subjects: | |
| Online Access: | http://www.molecular-cancer.com/content/11/1/47 |