The involvement of ADAR1 in chronic unpredictable stress-induced cognitive impairment by targeting DARPP-32 with miR-874-3p in BALB/c mice

Introduction: Chronic stress exposure is the main environmental factor leading to cognitive impairment, but the detailed molecular mechanism is still unclear. Adenosine Deaminase acting on double-stranded RNA1(ADAR1) is involved in the occurrence of chronic stress-induced cognitive impairment. In ad...

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Main Authors: Yanfang Wang, Yingxin Liu, Ziwei Zhao, Xinyu Wu, Jiabin Lin, Yufei Li, Wei Yan, Yi Wu, Yanfei Shi, Xindi Wu, Ying Xue, Jiaqian He, Shuqi Liu, Xiaonan Zhang, Hong Xu, Yiyuan Tang, Shengming Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.919297/full