Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice

Astragaloside IV improves renal function and fibrosis via inhibition of miR-21-induced podocyte dedifferentiation and mesangial cell activation in diabetic mice

Xiaolei Wang,1,2 Yanbin Gao,1,2 Nianxiu Tian,1 Dawei Zou,2 Yimin Shi,1 Nan Zhang1,2 1Department of Endocrinology, School of Traditional Chinese Medicine, Capital Medical University, Beijing, China; 2Department of Endocrinology, Beijing Key Laboratory of Traditional Chinese Medicine Collateral Disea...

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Bibliographic Details
Main Authors: Wang X, Gao Y, Tian N, Zou D, Shi Y, Zhang N
Format: Article
Language:English
Published: Dove Medical Press 2018-08-01
Series:Drug Design, Development and Therapy
Subjects:
Astragalosides IV
podocyte dedifferentiation
mesangial cell activation
miR-21
β-catenin pathway
TGF-β1/smads pathway
renal fibrosis
Online Access:https://www.dovepress.com/astragaloside-iv-improves-renal-function-and-fibrosis-via-inhibition-o-peer-reviewed-article-DDDT

Internet

https://www.dovepress.com/astragaloside-iv-improves-renal-function-and-fibrosis-via-inhibition-o-peer-reviewed-article-DDDT

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