Structurally Different Yet Functionally Similar: Aptamers Specific for the Ebola Virus Soluble Glycoprotein and GP1,2 and Their Application in Electrochemical Sensing

Structurally Different Yet Functionally Similar: Aptamers Specific for the Ebola Virus Soluble Glycoprotein and GP1,2 and Their Application in Electrochemical Sensing

The Ebola virus glycoprotein (GP) gene templates several mRNAs that produce either the virion-associated transmembrane protein or one of two secreted glycoproteins. Soluble glycoprotein (sGP) is the predominant product. GP1 and sGP share an amino terminal sequence of 295 amino acids but differ in qu...

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Bibliographic Details
Main Authors: Soma Banerjee, Mahsa Askary Hemmat, Shambhavi Shubham, Agnivo Gosai, Sivaranjani Devarakonda, Nianyu Jiang, Charith Geekiyanage, Jacob A. Dillard, Wendy Maury, Pranav Shrotriya, Monica H. Lamm, Marit Nilsen-Hamilton
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
aptamers
Ebola GP1,2
Ebola sGP
electrochemical sensor
aptamer–protein interaction
Online Access:https://www.mdpi.com/1422-0067/24/5/4627

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https://www.mdpi.com/1422-0067/24/5/4627

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