Diversification of gene content in the Mycobacterium tuberculosis complex is determined by phylogenetic and ecological signatures

ABSTRACTWe analyzed the pan-genome and gene content modulation of the most diverse genome data set of the Mycobacterium tuberculosis complex (MTBC) gathered to date. The closed pan-genome of the MTBC was characterized by reduced accessory and strain-specific genomes, compatible with its clonal natur...

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Bibliographic Details
Main Authors: Taiana Tainá Silva-Pereira, Naila Cristina Soler-Camargo, Ana Marcia Sá Guimarães
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02289-23