Diversification of gene content in the Mycobacterium tuberculosis complex is determined by phylogenetic and ecological signatures

Diversification of gene content in the Mycobacterium tuberculosis complex is determined by phylogenetic and ecological signatures

ABSTRACTWe analyzed the pan-genome and gene content modulation of the most diverse genome data set of the Mycobacterium tuberculosis complex (MTBC) gathered to date. The closed pan-genome of the MTBC was characterized by reduced accessory and strain-specific genomes, compatible with its clonal natur...

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Bibliographic Details
Main Authors: Taiana Tainá Silva-Pereira, Naila Cristina Soler-Camargo, Ana Marcia Sá Guimarães
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
genomics
pan-genome
Mycobacterium bovis
Mycobacterium africanum
evolution
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02289-23

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