Phage spanins: diversity, topological dynamics and gene convergence

Phage spanins: diversity, topological dynamics and gene convergence

Abstract Background Spanins are phage lysis proteins required to disrupt the outer membrane. Phages employ either two-component spanins or unimolecular spanins in this final step of Gram-negative host lysis. Two-component spanins like Rz-Rz1 from phage lambda consist of an integral inner membrane pr...

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Bibliographic Details
Main Authors: Rohit Kongari, Manoj Rajaure, Jesse Cahill, Eric Rasche, Eleni Mijalis, Joel Berry, Ry Young
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Bioinformatics
Subjects:
Bacteriophage lysis
Spanins
Membrane fusion
Gene evolution
Secondary structure predictions
Genetic architecture
Online Access:http://link.springer.com/article/10.1186/s12859-018-2342-8

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http://link.springer.com/article/10.1186/s12859-018-2342-8

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