Neural Progenitor Cells Expressing Herpes Simplex Virus-Thymidine Kinase for Ablation Have Differential Chemosensitivity to Brivudine and Ganciclovir

Neural Progenitor Cells Expressing Herpes Simplex Virus-Thymidine Kinase for Ablation Have Differential Chemosensitivity to Brivudine and Ganciclovir

Neural progenitor cell (NPC) transplants are a promising therapy for treating spinal cord injury (SCI), however, their long-term role after engraftment and the relative contribution to ongoing functional recovery remains a key knowledge gap. Selective human cell ablation techniques, currently being...

Full description

Bibliographic Details
Main Authors: Zijian Lou, Alexander Post, Christopher E. Rodgers, Mahmood Chamankhah, James Hong, Christopher S. Ahuja, Mohamad Khazaei, Michael G. Fehlings
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spinal cord injury
cell ablation
neural progenitor cell
ganciclovir
induced pluripotent stem cells
brivudine
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.638021/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.638021/full

Similar Items