Microglia promote remyelination independent of their role in clearing myelin debris

Microglia promote remyelination independent of their role in clearing myelin debris

Summary: Multiple sclerosis (MS) is an inflammatory disease characterized by myelin loss. While therapies exist to slow MS progression, no treatment currently exists for remyelination. Remyelination, linked to reduced disability in MS, relies on microglia and monocyte-derived macrophages (MDMs). Thi...

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Bibliographic Details
Main Authors: Charbel S. Baaklini, Madelene F.S. Ho, Tristan Lange, Brady P. Hammond, Sharmistha P. Panda, Martin Zirngibl, Sameera Zia, Kassandre Himmelsbach, Heli Rana, Braxton Phillips, Daria Antoszko, Jeremies Ibanga, Mizuki Lopez, Kelly V. Lee, Michael B. Keough, Andrew V. Caprariello, Bradley J. Kerr, Jason R. Plemel
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723015863

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http://www.sciencedirect.com/science/article/pii/S2211124723015863

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