Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis

STATs (Signal Transducers and Activators of Transcription) 5A and 5B are induced during adipocyte differentiation and are primarily activated by growth hormone (GH) and prolactin in fat cells. Previous studies in mice lacking adipocyte GH receptor or STAT5 support their roles in lipolysis-mediated r...

Full description

Bibliographic Details
Main Authors: Allison J. Richard, Hardy Hang, Timothy D. Allerton, Peng Zhao, Tamra Mendoza, Sujoy Ghosh, Carrie M. Elks, Jacqueline M. Stephens
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Endocrinology
Subjects:
adipose
STATs
sexual dimorphism
growth hormone
transcription
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.812802/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.812802/full

Similar Items