Lysophosphatidic Acid Promotes the Expansion of Cancer Stem Cells via TRPC3 Channels in Triple-Negative Breast Cancer

Lysophosphatidic Acid Promotes the Expansion of Cancer Stem Cells via TRPC3 Channels in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a highly aggressive cancer for which targeted therapeutic agents are limited. Growing evidence suggests that TNBC originates from breast cancer stem cells (BCSCs), and elucidation of the molecular mechanisms controlling BCSC proliferation will be crucial for n...

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Bibliographic Details
Main Authors: Naoya Hirata, Shigeru Yamada, Shota Yanagida, Atsushi Ono, Yukuto Yasuhiko, Motohiro Nishida, Yasunari Kanda
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
lysophosphatidic acid
cancer stem cells
transient receptor potential cation channel subfamily C member 3
nuclear factor of activated T cells
triple-negative breast cancer
Online Access:https://www.mdpi.com/1422-0067/23/4/1967

Internet

https://www.mdpi.com/1422-0067/23/4/1967

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