MiRNA-21 promotes differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells by regulating the Ajuba/Isl1 axis pathway

Introduction In this study, we aimed to investigate the role of miRNA-21 and the regulating pathway that promotes the differentiation of bone marrow mesenchymal stem cells (BMSCs). Material and methods We used miR-21-OE, miR-21-KD, ajuba-OE and ajuba-KD plasmids to infect BMSCs. The expression of m...

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Bibliographic Details
Main Authors: Wengang Yang, Lei Zhao, Song Xue, Jidong Liu, Jianggui Shan
Format: Article
Language:English
Published: Termedia Publishing House 2022-11-01
Series:Archives of Medical Science
Subjects:
Online Access:https://www.archivesofmedicalscience.com/MiRNA-21-promotes-differentiation-of-bone-marrow-mesenchymal-stem-cells-into-cardiomyocyte,154956,0,2.html