Exosomal miR-328 originated from pulmonary adenocarcinoma cells enhances osteoclastogenesis via downregulating Nrp-2 expression

Abstract Osseous metastases of pulmonary carcinoma and the detailed mechanisms remain unclear, and the effects of exosomes (Exos) originated from pulmonary adenocarcinoma cells in this process have received a lot of attentions. Our study revealed that the Exos secreted from A549 cells (A549-Exos) en...

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Bibliographic Details
Main Authors: Chengcheng Zhang, Jingru Qin, Lu Yang, Zhiyao Zhu, Jia Yang, Wan Su, Haibin Deng, Zhongqi Wang
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01194-z