Intrinsically-disordered N-termini in human parechovirus 1 capsid proteins bind encapsidated RNA
Abstract Human parechoviruses (HPeV) are picornaviruses with a highly-ordered RNA genome contained within icosahedrally-symmetric capsids. Ordered RNA structures have recently been shown to interact with capsid proteins VP1 and VP3 and facilitate virus assembly in HPeV1. Using an assay that combines...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-018-23552-7 |