Intrinsically-disordered N-termini in human parechovirus 1 capsid proteins bind encapsidated RNA

Intrinsically-disordered N-termini in human parechovirus 1 capsid proteins bind encapsidated RNA

Abstract Human parechoviruses (HPeV) are picornaviruses with a highly-ordered RNA genome contained within icosahedrally-symmetric capsids. Ordered RNA structures have recently been shown to interact with capsid proteins VP1 and VP3 and facilitate virus assembly in HPeV1. Using an assay that combines...

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Bibliographic Details
Main Authors: Shabih Shakeel, James D. Evans, Mark Hazelbaker, C. Cheng Kao, Robert C. Vaughan, Sarah J. Butcher
Format: Article
Language:English
Published: Nature Portfolio 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-23552-7

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