<named-content content-type="genus-species">Chlamydia trachomatis</named-content> Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

ABSTRACT The cytokine gamma interferon (IFN-γ) induces cell-autonomous immunity to combat infections with intracellular pathogens, such as the bacterium Chlamydia trachomatis. The present study demonstrates that IFN-γ-primed human cells ubiquitinate and eliminate intracellular Chlamydia-containing v...

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Bibliographic Details
Main Authors: Arun K. Haldar, Anthony S. Piro, Ryan Finethy, Scott T. Espenschied, Hannah E. Brown, Amanda M. Giebel, Eva-Maria Frickel, David E. Nelson, Jörn Coers
Format: Article
Language:English
Published: American Society for Microbiology 2016-12-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01417-16