Improved genetically encoded near-infrared fluorescent calcium ion indicators for in vivo imaging.

Near-infrared (NIR) genetically encoded calcium ion (Ca2+) indicators (GECIs) can provide advantages over visible wavelength fluorescent GECIs in terms of reduced phototoxicity, minimal spectral cross talk with visible light excitable optogenetic tools and fluorescent probes, and decreased scatterin...

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Bibliographic Details
Main Authors: Yong Qian, Danielle M Orozco Cosio, Kiryl D Piatkevich, Sarah Aufmkolk, Wan-Chi Su, Orhan T Celiker, Anne Schohl, Mitchell H Murdock, Abhi Aggarwal, Yu-Fen Chang, Paul W Wiseman, Edward S Ruthazer, Edward S Boyden, Robert E Campbell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000965