SARS-CoV-2 spike-reactive naïve B cells and pre-existing memory B cells contribute to antibody responses in unexposed individuals after vaccination

SARS-CoV-2 spike-reactive naïve B cells and pre-existing memory B cells contribute to antibody responses in unexposed individuals after vaccination

IntroductionSince December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) has presented considerable public health challenges. Multiple vaccines have been used to induce neutralizing antibodies (nAbs) and memory B-cell...

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Bibliographic Details
Main Authors: Shishan Teng, Yabin Hu, You Wang, Yinggen Tang, Qian Wu, Xingyu Zheng, Rui Lu, Dong Pan, Fen Liu, Tianyi Xie, Chanfeng Wu, Yi-Ping Li, Wenpei Liu, Xiaowang Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
naïve B cell
preexisting memory B cell
vaccination
monoclonal antibody
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355949/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355949/full

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