Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma

Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma

Abstract Cholangiocarcinomas (CCAs) are rare but aggressive tumors of the bile ducts. CCAs are often diagnosed at an advanced stage and respond poorly to current conventional radiotherapy and chemotherapy. High mobility group A1 (HMGA1) is an architectural transcription factor that is overexpressed...

Full description

Bibliographic Details
Main Authors: Jianping Song, Donghai Cui, Jing Wang, Junchao Qin, Shourong Wang, Zixiang Wang, Xiangyu Zhai, Huan Ma, Delin Ma, Yanfeng Liu, Bin Jin, Zhaojian Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00721-8

Internet

https://doi.org/10.1038/s41420-021-00721-8

Similar Items