Preliminary verification of the anti-hypoxia mechanism of Gentiana straminea maxim based on UPLC-triple TOF MS/MS and network pharmacology

Preliminary verification of the anti-hypoxia mechanism of Gentiana straminea maxim based on UPLC-triple TOF MS/MS and network pharmacology

Abstract Background Anoxia is characterized by changes in the morphology, metabolism, and function of tissues and organs due to insufficient oxygen supply or oxygen dysfunction. Gentiana straminea Maxim (G.s Maxim) is a traditional Tibetan medicine. Our previous work found that G.s Maxim mediates re...

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Bibliographic Details
Main Authors: Xiu mei Kong, Dan Song, Jie Li, Yi Jiang, Xiao ying Zhang, Xiao Jun Wu, Ming juan Ge, Jiao jiao Xu, Xiao min Gao, Qin Zhao
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Complementary Medicine and Therapies
Subjects:
G.s Maxim’s ethyl acetate extraction
Anti- hypoxia
Network pharmacology
Inflammatory
HIF-1/NF-κB pathway
Online Access:https://doi.org/10.1186/s12906-022-03773-0

Internet

https://doi.org/10.1186/s12906-022-03773-0

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