Menin orchestrates hepatic glucose and fatty acid uptake via deploying the cellular translocation of SIRT1 and PPARγ

Menin orchestrates hepatic glucose and fatty acid uptake via deploying the cellular translocation of SIRT1 and PPARγ

Abstract Background Menin is a scaffold protein encoded by the Men1 gene, which interacts with various transcriptional proteins to activate or repress cellular processes and is a key mediator in multiple organs. Both liver-specific and hepatocyte-specific Menin deficiency promotes high-fat diet-indu...

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Bibliographic Details
Main Authors: Tingjun Liu, Ranran Li, Lili Sun, Zhongjin Xu, Shengxuan Wang, Jingxuan Zhou, Xuanning Wu, Kerong Shi
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Cell & Bioscience
Subjects:
Menin
Hepatocytes
PPARγ
SIRT1
NAFLD
Metabolism homeostatsis
Online Access:https://doi.org/10.1186/s13578-023-01119-y

Internet

https://doi.org/10.1186/s13578-023-01119-y

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