Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT1R expression in rostral ventrolateral medulla

Renal sympathetic denervation lowers arterial pressure in canines with obesity-induced hypertension by regulating GAD65 and AT1R expression in rostral ventrolateral medulla

To explore the roles of glutamate acid decarboxylase 65 (GAD65) and angiotensin II type 1 receptor (AT1R) in the action of renal sympathetic denervation (RSD) on obesity-induced hypertension in canines. Thirty-two beagles were randomly divided into a hypertensive model (n = 22) and control (n = 10)...

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Bibliographic Details
Main Authors: Zhijie Shen, Chunyan Weng, Zhihui Zhang, Xiaoyan Wang, Kan Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Clinical and Experimental Hypertension
Subjects:
at1r
gad65
gamma amino acid butyric acid
hypertension
renal sympathetic denervation
rostral ventrolateral medulla
Online Access:http://dx.doi.org/10.1080/10641963.2017.1306542

Internet

http://dx.doi.org/10.1080/10641963.2017.1306542

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