Involvement of Pore Formation and Osmotic Lysis in the Rapid Killing of Gamma Interferon-Pretreated C166 Endothelial Cells by <i>Rickettsia prowazekii</i>

<i>Rickettsia prowazekii</i>, the bacterial cause of epidemic typhus in humans, proliferates mainly within the microvascular endothelial cells. Previous studies have shown that murine macrophage-like RAW264.7 cells are rapidly damaged if they are pretreated with gamma interferon (IFN-γ)...

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Bibliographic Details
Main Author: Jenifer Turco
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Tropical Medicine and Infectious Disease
Subjects:
Online Access:https://www.mdpi.com/2414-6366/7/8/163