Global profiling of protein lactylation in microglia in experimental high-altitude cerebral edema

Global profiling of protein lactylation in microglia in experimental high-altitude cerebral edema

Abstract Background High-altitude cerebral edema (HACE) is considered an end-stage acute mountain sickness (AMS) that typically occurs in people after rapid ascent to 2500 m or more. While hypoxia is a fundamental feature of the pathophysiological mechanism of HACE, emerging evidence suggests that i...

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Bibliographic Details
Main Authors: Xiufang Jiang, Jiayue Gao, Xuechao Fei, Yanan Geng, Xiangpei Yue, Zibi Shi, Xiang Cheng, Tong Zhao, Ming Fan, Haitao Wu, Ming Zhao, Lingling Zhu
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Cell Communication and Signaling
Subjects:
Lactylation
High altitude cerebral edema (HACE)
Inflammation
Microglia
Online Access:https://doi.org/10.1186/s12964-024-01748-x

Internet

https://doi.org/10.1186/s12964-024-01748-x

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