A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers.

<h4>Background and aims</h4>Unnatural self-organizing biomimetic polymers (foldamers) emerged as promising materials for biomolecule recognition and inhibition. Our goal was to construct multivalent foldamer-dendrimer conjugates which wrap the synaptotoxic β-amyloid (Aβ) oligomers with h...

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Bibliographic Details
Main Authors: Lívia Fülöp, István M Mándity, Gábor Juhász, Viktor Szegedi, Anasztázia Hetényi, Edit Wéber, Zsolt Bozsó, Dóra Simon, Mária Benkő, Zoltán Király, Tamás A Martinek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22859942/?tool=EBI