Targeting mTORC1 Activity to Improve Efficacy of Radioligand Therapy in Cancer

Targeting mTORC1 Activity to Improve Efficacy of Radioligand Therapy in Cancer

Radioligand therapy (RLT) represents an effective strategy to treat malignancy by cancer-selective delivery of radioactivity following systemic application. Despite recent therapeutic successes, cancer radioresistance and insufficient delivery of the radioactive ligands, as well as cytotoxicity to h...

Full description

Bibliographic Details
Main Authors: Michal Grzmil, Fabius Wiesmann, Roger Schibli, Martin Behe
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
targeted radionuclide therapy
TRT
radioligand therapy
RLT
PRRT
mammalian target of rapamycin
Online Access:https://www.mdpi.com/2072-6694/15/1/17

Internet

https://www.mdpi.com/2072-6694/15/1/17

Similar Items