Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses.

Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses.

Retinal Müller glia (MG) can act as stem-like cells to generate new neurons in both zebrafish and mice. In zebrafish, retinal regeneration is innate and robust, resulting in the replacement of lost neurons and restoration of visual function. In mice, exogenous stimulation of MG is required to reveal...

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Main Authors: Kevin Emmerich, Steven L Walker, Guohua Wang, David T White, Anneliese Ceisel, Fang Wang, Yong Teng, Zeeshaan Chunawala, Gianna Graziano, Saumya Nimmagadda, Meera T Saxena, Jiang Qian, Jeff S Mumm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010905&type=printable

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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010905&type=printable

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