Shunting inhibition controls the gain modulation mediated by asynchronous neurotransmitter release in early development.

The sensitivity of a neuron to its input can be modulated in several ways. Changes in the slope of the neuronal input-output curve depend on factors such as shunting inhibition, background noise, frequency-dependent synaptic excitation, and balanced excitation and inhibition. However, in early devel...

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Bibliographic Details
Main Authors: Vladislav Volman, Herbert Levine, Terrence J Sejnowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2973817?pdf=render