Expression of inhibin-alpha is regulated synergistically by Wilms' tumor gene 1 (Wt1) and steroidogenic factor-1 (Sf1) in sertoli cells.

Wt1 encodes a zinc finger nuclear transcriptional factor, which is specifically expressed in testicular Sertoli cells and knockdown of Wt1 in Sertoli cells causes male mice subfertility. However, the underlying mechanism is still unclear. In this study, we found that expression of inhibin-α is signi...

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Bibliographic Details
Main Authors: Shao-Yang Ji, Jian-Xiu Hao, Lei Li, Jun Zhang, Qiao-Song Zheng, Xi-Xia Li, Xiao-Na Wang, Chun-Sheng Han, Fei Gao, Yi-Xun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543449?pdf=render