Establishment of human embryonic stem cell WAe009-A-74 carrying a Long QT syndrome mutation in KCNH2

Long-QT syndrome type 2 (LQT2) is a common malignant hereditary arrhythmia. Due to the lack of suitable animal and human models, the pathogenesis of LQT2 caused by human ether-a-go-go-related gene (hERG) deficiency is still unclear. Herein, we have generated a human embryonic stem cell line (WAe009-...

Full description

Bibliographic Details
Main Authors: Lixiang Sun, Jiaqi Zhong, Fujian Wu, Furong Li, Xiaofei Yang, Zhiyu Zeng
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122000745