Kidney derived apolipoprotein M and its role in acute kidney injury

Aim: Apolipoprotein M (apoM) is mainly expressed in liver and in proximal tubular epithelial cells in the kidney. In plasma, apoM associates with HDL particles via a retained signal peptide and carries sphingosine-1-phosphate (S1P), a small bioactive lipid. ApoM is undetectable in urine from healthy...

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Bibliographic Details
Main Authors: Line S. Bisgaard, Pernille M. Christensen, Jeongah Oh, Federico Torta, Ernst-Martin Füchtbauer, Lars Bo Nielsen, Christina Christoffersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1328259/full