Long-term administration of CU06-1004 ameliorates cerebrovascular aging and BBB injury in aging mouse model
Abstract Background Age-related changes in the cerebrovasculature, including blood–brain barrier (BBB) disruption and vascular dementia, are emerging as potential risks for many neurodegenerative diseases. Therefore, the endothelial cells that constitute the cerebrovasculature may play key roles in...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-02-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12987-023-00410-x |