The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia
Genetic lesions affecting polycomb repressive complex 2 (PRC2) have been found in more than 40% of pediatric cases of early T-cell precursor acute lymphoblastic leukemia. The functional role of these PRC2 alterations has been obscure. Our recent data suggest that compromise of PRC2 blocks differenti...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2018-09-01
|
| Series: | Molecular & Cellular Oncology |
| Online Access: | http://dx.doi.org/10.1080/23723556.2016.1166309 |