9-oxo-ODAs suppresses the proliferation of human cervical cancer cells through the inhibition of CDKs and HPV oncoproteins

Abstract Mucosal human papillomavirus (HPV) subtypes 16 and 18 are causative agents of cervical cancer, a leading cause of cancer-related deaths among women worldwide. In Japan, eggplant calyx is a folk remedy used to treat common warts. 9-oxo-(10E,12E)-octadecadienoic acid, isolated from eggplant c...

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Bibliographic Details
Main Authors: Kazumasa Mogi, Yoshihiro Koya, Masato Yoshihara, Mai Sugiyama, Rika Miki, Emiri Miyamoto, Hiroki Fujimoto, Kazuhisa Kitami, Shohei Iyoshi, Sho Tano, Kaname Uno, Satoshi Tamauchi, Akira Yokoi, Yusuke Shimizu, Yoshiki Ikeda, Nobuhisa Yoshikawa, Kaoru Niimi, Yoshihiko Yamakita, Hiroyuki Tomita, Kiyosumi Shibata, Akihiro Nawa, Yutaka Tomoda, Hiroaki Kajiyama
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44365-3