Deciphering the role of LGALS2: insights into tertiary lymphoid structure-associated dendritic cell activation and immunotherapeutic potential in breast cancer patients

Deciphering the role of LGALS2: insights into tertiary lymphoid structure-associated dendritic cell activation and immunotherapeutic potential in breast cancer patients

Abstract Recent advances in cancer research have highlighted the pivotal role of tertiary lymphoid structures (TLSs) in modulating immune responses, particularly in breast cancer (BRCA). Here, we performed an integrated analysis of bulk transcriptome data from over 6000 BRCA samples using biological...

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Bibliographic Details
Main Authors: Shuyu Li, Nan Zhang, Hao Zhang, Zhifang Yang, Quan Cheng, Kang Wei, Meng Zhou, Chenshen Huang
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Molecular Cancer
Subjects:
LGALS2
Breast cancer immunotherapy
Tertiary lymphoid structures
Dendritic cell activation
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12943-024-02126-4

Internet

https://doi.org/10.1186/s12943-024-02126-4

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