Starvation of low-density lipoprotein-derived cholesterol induces bradyzoite conversion in Toxoplasma gondii

Abstract Background Lacking enzymes for sterol synthesis, the intracellular protozoan Toxoplasma gondii scavenges cholesterol from host cells to multiply. T. gondii has a complex life cycle consisting of two asexual stages; the proliferative stage (tachyzoite), and the latent stage characterized by...

Full description

Bibliographic Details
Main Authors: Fumiaki Ihara, Yoshifumi Nishikawa
Format: Article
Language:English
Published: BMC 2014-05-01
Series:Parasites & Vectors
Subjects:
Online Access:https://doi.org/10.1186/1756-3305-7-248