Synthetic 1,4-pyran naphthoquinones are potent inhibitors of dengue virus replication.

Dengue virus infection is a serious public health problem in endemic areas of the world where 2.5 billion people live. Clinical manifestations of the Dengue infection range from a mild fever to fatal cases of hemorrhagic fever. Although being the most rapidly spreading mosquito-borne viral infection...

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Bibliographic Details
Main Authors: Emmerson C B da Costa, Raquel Amorim, Fernando C da Silva, David R Rocha, Michelle P Papa, Luciana B de Arruda, Ronaldo Mohana-Borges, Vitor F Ferreira, Amilcar Tanuri, Luciana J da Costa, Sabrina B Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869945?pdf=render