Synthetic 1,4-pyran naphthoquinones are potent inhibitors of dengue virus replication.
Dengue virus infection is a serious public health problem in endemic areas of the world where 2.5 billion people live. Clinical manifestations of the Dengue infection range from a mild fever to fatal cases of hemorrhagic fever. Although being the most rapidly spreading mosquito-borne viral infection...
Main Authors: | Emmerson C B da Costa, Raquel Amorim, Fernando C da Silva, David R Rocha, Michelle P Papa, Luciana B de Arruda, Ronaldo Mohana-Borges, Vitor F Ferreira, Amilcar Tanuri, Luciana J da Costa, Sabrina B Ferreira |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3869945?pdf=render |
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