Development of a Curcumin-Loaded Lecithin/Chitosan Nanoparticle Utilizing a Box-Behnken Design of Experiment: Formulation Design and Influence of Process Parameters

Development of a Curcumin-Loaded Lecithin/Chitosan Nanoparticle Utilizing a Box-Behnken Design of Experiment: Formulation Design and Influence of Process Parameters

Curcumin (CUR) has impressive pharmacologic properties, including cardioprotective, neuroprotective, antimicrobial, and anticancer activity. However, the pharmaceutical application of CUR is limited due to its poor aqueous solubility and low bioavailability. The development of novel formulations has...

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Bibliographic Details
Main Authors: Ismail A. Walbi, Mohammad Zaki Ahmad, Javed Ahmad, Mohammed S. Algahtani, Amer S. Alali, Samar A. Alsudir, Alhassan H. Aodah, Hassan A. Albarqi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Polymers
Subjects:
curcumin
chitosan
lecithin
nanoparticles
stirring speed
3-factorial Box-Behnken statistical design
Online Access:https://www.mdpi.com/2073-4360/14/18/3758

Internet

https://www.mdpi.com/2073-4360/14/18/3758

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