Lipid Specific Membrane Interaction of Aptamers and Cytotoxicity

Lipid Specific Membrane Interaction of Aptamers and Cytotoxicity

We aim to discover diagnostic tools to detect phosphatidylserine (PS) externalization on apoptotic cell surface using PS binding aptamers, AAAGAC and TAAAGA, and hence to understand chemotherapy drug efficacy when inducing apoptosis into cancer cells. The entropic fragment-based approach designed ap...

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Bibliographic Details
Main Authors: Md. Ashrafuzzaman, Hanouf A. M. AlMansour, Maha A. S. AlOtaibi, Zahid Khan, Gouse M. Shaik
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Membranes
Subjects:
aptamer
phosphatidylserine
membrane
cell
cytotoxicity
Online Access:https://www.mdpi.com/2077-0375/12/1/37

Internet

https://www.mdpi.com/2077-0375/12/1/37

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